Denise Monack, Ph. D.
Denise M. Monack is currently an Associate Professor at Stanford University. She received her B.S. in Genetics from the University of California at Davis, followed by Ph.D. in Microbiology and Immunology from Stanford University, and postdoctoral studies at Stanford University with Dr. Stanley Falkow in the field of bacterial pathogenesis. Monack’s research focuses on understanding complex host-pathogen interactions at the genetic and molecular level, with a focus on understanding heterogeneity in infections at single cell and host levels. In particular, her discoveries that Salmonella kills macrophages formed the foundation for research on the inflammasome, a host pro-inflammatory response. In addition, Dr. Monack’s lab studies the heterogeneity in hosts that are chronically infected with Salmonella where some hosts readily transmit disease, termed superspreaders. Their finding that superspreaders possess a unique dampened immune state has been reported in the Wall Street Journal and other media outlets worldwide. Dr. Monack’s work has received several awards, including Baxter Faculty Scholar, Donald E. and Delia B. Baxter Foundation (2008), The Burroughs Wellcome Fund Recipient in Infectious Disease (2009), Society of Leukocyte Biology G.J. Thorbecke Award (2010), and she is an elected Fellow to the American Academy of Microbiology (2015).
The Monack Lab